Publications

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration and Soft Tissue Attachment In Vivo

Han, P., Liu, C., Jayasree, A., Sokolowski, K., Liaw, A., Liu, D., Salomon, C., Gulati, K., Lee, R. S., Huang, B., & Ivanovski, S.

Advanced Healthcare Materials · 2026 · Vol. 15(13)

Multi-omics analysis of uterine fluid extracellular vesicles reveals a resemblance with endometrial tissue across the menstrual cycle: biological and translational insights

Apostolov A., Mladenović, D., Tilk, K., Lõhmus, A., Vesselin Baev, Yahubyan, G., Sola-Leyva, A., Bergamelli, M., André Görgens, Zhao, C., Samir E L Andaloussi, Aive Kalinina, Acharya, G., Lanner, F., Merli Saare, Peters, M., Piomboni, P., Luddi, A., Salumets, A., & Aleksejeva, E.

Human Reproduction Open · 2025 · Vol. 2025(2)

Enhanced yield and proteomic profile of osteoblast-derived extracellular vesicles from 3D MEW mPCL scaffolds

Liu, C., Zhang, C., Hua, S., Salomon, C., Sašo Ivanovski, & Han, P.

Journal of Materials Chemistry B · 2025 · Vol. 13(26)

Comparing the Proteomic Profiles of Extracellular Vesicles Isolated using Different Methods from Long-term Stored Plasma Samples

Torres, A., Bernardo, L., Sánchez, C., Morato, E., Solana, J. C., & Carrillo, E.

Biological Procedures Online · 2024 · Vol. 26(1)

Mitochondrial DNA deletions in the cerebrospinal fluid of patients with idiopathic REM sleep behaviour disorder

Puigròs, M., Calderon, A., Martín-Ruiz, D., Serradell, M., Fernández, M., Muñoz-Lopetegi, A., Mayà, G., Santamaria, J., Gaig, C., Colell, A., Tolosa, E., Iranzo, A., & Trullas, R.

eBioMedicine · 2024 · Vol. 102

3D bioprinted small extracellular vesicles from periodontal cells enhance mesenchymal stromal cell function

Han, P., Raveendran, N., Liu, C., Basu, S., Jiao, K., Johnson, N., Moran, C. S., & Ivanovski, S.

Biomaterials Advances · 2024 · Vol. 158

Neurotoxic effects of coronavirus: Potential implications in Alzheimer’s onset and progression

Beretti, F., Gatti, M., Ricchi, F., Lipani, F., Cortelli, P., Cermelli, C., & Maraldi, T.

Experimental Neurology · 2024 · Vol. 380(114908)

Immunomodulatory effects of MDA-MB-231-derived exosome mimetic nanovesicles on CD4+ T cell line

Mustafa Oztatlici, Alper Tunga Ozdemir, Hulya Oztatlici, Serife Kucukhuyuk, Rabia Bilge Ozgul Ozdemir, Hilmi Orhan, Kemal Ozbilgin

Eurasian Journal of Medicine and Oncology · 2024 · Vol. 8(1)

Benefits of FAIMS to improve the proteome coverage of deteriorated and/or Cross-Linked TMT 10-Plex FFPE tissue and Plasma-Derived exosomes samples

Montero-Calle, A., Garranzo-Asensio, M., Rejas-González, R., Feliu, J., Mendiola, M., Peláez-García, A., & Barderas, R.

Proteomes · 2023 · Vol. 11(4)

Microglial-Targeted NSMASE2 inhibitor fails to reduce TAU propagation in PS19 mice

Huang, M., Tallon, C., Zhu, X., Huizar, K. D. J., Picciolini, S., Thomas, A. G., Tenora, L., Liyanage, W., Rodà, F., Gualerzi, A., Kannan, R. M., Bedoni, M., Rais, R., & Slusher, B. S.

Pharmaceutics · 2023 · Vol. 15(9)

Immobilization of biotinylated antibodies through streptavidin binding aptamer

Brambilla, D., Sola, L., Damin, F., Mussida, A., & Chiari, M.

Talanta · 2023 · Vol. 265(124847)

Effects of periodontal cells‐derived extracellular vesicles on mesenchymal stromal cell function

Han, P., Johnson, N., Abdal‐hay, A., Moran, C. S., Salomon, C., & Ivanovski, S.

Journal of Periodontal Research · 2023 · Vol. 58(6)

Microvesicle-eluting nano-engineered implants influence inflammatory response of keratinocytes

Jayasree, A., Liu, C., Salomon, C., Ivanovski, S., Gulati, K., & Han, P.

Drug Delivery and Translational Research · 2023 · Vol. 14

Immunoaffinity-enriched salivary small extracellular vesicles in periodontitis

Liu, C., Seneviratne, C. J., Palma, C., Rice, G., Salomon, C., Khanabdali, R., Ivanovski, S., & Han, P.

Extracellular Vesicles and Circulating Nucleic Acids · 2023 · Vol. 4(4)

Multiplexing Biosensor for the Detection of Extracellular Vesicles as Biomarkers of Tissue Damage and Recovery after Ischemic Stroke

Picciolini S, Mangolini V, Rodà F, Montesano A, Arnaboldi F, Liuzzi P, Mannini A, Bedoni M, Gualerzi A.

International Journal of Molecular Sciences · 2023 · Vol. 24(9)

Infrared and Raman spectroscopy for purity assessment of extracellular vesicles

Zini, J., Saari, H., Ciana, P., Viitala, T., Lõhmus, A., Saarinen, J., & Yliperttula, M.

European Journal of Pharmaceutical Sciences · 2022 · Vol. 172(106135)

Advantageous antibody microarray fabrication through DNA-directed immobilization: a step toward use of extracellular vesicles in diagnostics

Brambilla D, Sola L, Chiari M.

Talanta · 2021 · Vol. 222(121542)

An SPRi-based biosensor pilot study: Analysis of multiple circulating extracellular vesicles and hippocampal volume in Alzheimer’s disease

Picciolini, S., Gualerzi, A., Carlomagno, C., Cabinio, M., Sorrentino, S., Baglio, F., & Bedoni, M.

Journal of Pharmaceutical and Biomedical Analysis · 2020 · Vol. 192(113649)

Extracellular vesicles provide a capsid-free vector for oncolytic adenoviral DNA delivery

Saari H, Turunen T, Lõhmus A, Turunen M, Jalasvuori M, Butcher SJ, Ylä-Herttuala S, Viitala T, Cerullo V, Siljander PRM, Yliperttula M.

Journal of Extracellular Vesicles · 2020 · Vol. 9(1)

Rigorous characterization of urinary extracellular vesicles (uEVs) in the low centrifugation pellet-a neglected source for uEVs

Musante L, Bontha SV, La Salvia S, Fernandez-Piñeros A, Lannigan J, Le TH, Mas V, Erdbrügger U.

Scientific Reports · 2020 · Vol. 10(1)

Comparison of the therapeutic effect of amniotic fluid stem cells and their exosomes on monoiodoacetate‐induced animal model of osteoarthritis

Zavatti M, Beretti F, Casciaro F, Bertucci E, Maraldi T.

Biofactors · 2020 · Vol. 46(1)

Metabolic signature of extracellular vesicles depends on the cell culture conditions

Palviainen M, Saari H, Kärkkäinen O, Pekkinen J, Auriola S, Yliperttula M, Puhka M, Hanhineva K, Siljander PR.

Journal of Extracellular Vesicles · 2019 · Vol. 8(1)

Measuring zinc in biological nanovesicles by multiple analytical approaches

Francesco Piacenza, Antje Biesemeier, Marco Farina, Francesco Piva, Xin Jin, Eleonora Pavoni, Lorenzo Nisi, Maurizio Cardelli, Laura Costarelli, Robertina Giacconi, Andrea Basso, Elisa Pierpaoli, Mauro Provinciali, James C.M. Hwang, Antonio Morini, Andrea di Donato, Marco Malavolta

Journal of Trace Elements in Medicine and Biology · 2018 · Vol. 48

Low cardiorespiratory fitness is associated with higher extracellular vesicle counts in obese adults

Eichner NZM, Gilbertson NM, Gaitan JM, Heiston EM, Musante L, LaSalvia S, Weltman A, Erdbrügger U, Malin SK.

Physiological Reports · 2018 · Vol. 6(10)

Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats

Ohara M, Ohnishi S, Hosono H, Yamamoto K, Yuyama K, Nakamura H, Fu Q, Maehara O, Suda G, Sakamoto N.

Stem Cells International · 2018 · Vol. 2018

Human cytomegalovirus reactivation from latency: validation of a “switch” model in vitro

Arcangeletti MC, Vasile Simone R, Rodighiero I, De Conto F, Medici MC, Maccari C, Chezzi C, Calderaro A.

Virology Journal · 2016 · Vol. 13(1)

Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichmen

Musante L, Tataruch-Weinert D, Kerjaschki D, Henry M, Meleady P, Holthofer H.

Journal of Extracellular Vesicles · 2016 · Vol. 6(1)

Combined mass quantitation and phenotyping of intact extracellular vesicles by a microarray platform

Gagni P, Cretich M, Benussi L, Tonoli E, Ciani M, Ghidoni R, Santini B, Galbiati E, Prosperi D, Chiari M.

Analytica Chimica Acta · 2015 · Vol. 902

Micromagnet arrays for on-chip focusing, switching, and separation of superparamagnetic beads and single cells

Rampini, S., Kilinc, D., Li, P., Monteil, C., Gandhi, D., & Lee, G. U.

Lab on a Chip · 2015 · Vol. 15(16)

Quantification of EV-associated miRNA in liquid biopsies for biomarker signature development

Yu, M. S. C., Grätz, C., Chiang, D. M., Loudig, O., Zheng, Y., Hladik, C., Hannafon, B., Dogra, N., Kirchner, B., & Pfaffl, M. W.

Extracellular Vesicles and Circulating Nucleic Acids · 2026 · Vol. 7(2)

Cellular and biochemical heterogeneity contributes to the phenotypic diversity of transfusion-dependent beta thalassemia

Theocharaki, K., Anastasiadi, A. T., Delicou, S., Tzounakas, V. L., Barla, I., Rouvela, S., Kazolia, E., Tzafa, G., Mpekoulis, G., Gousdovas, T., Pavlou, E., Kostopoulos, I. V., Velentzas, A. D., Simantiris, N., Xydaki, A., Vassilaki, N., Voskaridou, E., Aggeli, I.-K., Nomikou, E., & Tsitsilonis, O.

Blood Advances · 2025 · Vol. 9(9)

The potential of exosomes in regenerative medicine and in the diagnosis and therapies of neurodegenerative diseases and cancer

Nikola Odehnalová, Viera Šandriková, Hromadka, R., Markéta Skaličková, Petr Dytrych, Hoskovec, D., Zdeněk Kejík, Hajduch, J., Frédéric Vellieux, Vašáková, M. K., Pavel Martásek, & Jakubek, M

Frontiers in Medicine · 2025 · Vol. 12

Dual facets of MSC-derived small EVs: regulatory insights into antitumor mechanisms in pancreatic ductal adenocarcinoma

Kaçaroğlu, D., Yaylacı, S., & Ulaşlı, A. M.

Medical Oncology · 2025 · Vol. 42(5)

Polyethylene glycol (PEG)-based precipitation for exosome enrichment: A review on recent developments, current challenges, and future perspectives

Marzouk, R. M. Gab-Allah, M. A., & Kim, J.

Analytical Science and Technology · 2025 · Vol. 38(2)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Papakonstantinou, D., Roumeliotou, A., Pantazaka, E., Shaukat, A., Christopoulou, A., Koutras, A., Dimitrakopoulos, F., Georgoulias, V., Xagara, A., Chantzara, E., Koinis, F., Kotsakis, A., Stathopoulos, C., & Kallergi, G.

Molecular Oncology · 2025 · Vol. 19(7)

Simultaneous isolation of intact brain cells and cell-specific extracellular vesicles from cryopreserved Alzheimer’s disease cortex

Melnik, M., Miyoshi, E., Ma, R., Corrada, M., Kawas, C., Bohannan, R., Caraway, C., Miller, C. A., Hinman, J. D., John, V., Bilousova, T., & Gylys, K. H.

Journal of Neuroscience Methods · 2024 · Vol. 406(110137)

Extracellular vesicles maintain Blood-Brain barrier integrity by the suppression of Caveolin-1/CD147/VEGFR2/MMP pathway after ischemic stroke

Li, Y., Chen, J., Quan, X., Chen, Y., Han, Y., Chen, J., Yang, L., Xu, Y., Shen, X., Wang, R., & Zhao, Y.

International Journal of Nanomedicine · 2024 · Vol. 19

The potential contribution of light-intensity exercise-induced miR-486a-3p secretion on enhancing empathic behavior in mice

Shima, T., Yoshii, K., Yoshikawa, Y., & Terashima, C.

Brain Research · 2024 · Vol. 1866(149923)

Bioactive glass-elicited stem cell-derived extracellular vesicles regulate M2 macrophage polarization and angiogenesis to improve tendon regeneration and functional recovery

Xu H, Zhu Y, Hsiao AW, Xu J, Tong W, Chang L, Zhang X, Chen YF, Li J, Chen W, Zhang Y, Chan HF, Lee CW

Biomaterials · 2023 · Vol. 294(121998)

Comparative study of extracellular vesicles derived from mesenchymal stem cells and brain endothelial cells attenuating blood–brain barrier permeability via regulating Caveolin-1-dependent ZO-1 and Claudin-5 endocytosis in acute ischemic stroke

Li Y, Liu B, Zhao T, Quan X, Han Y, Cheng Y, Chen Y, Shen X, Zheng Y, Zhao Y.

Journal of Nanobiotechnology · 2023 · Vol. 21(1)

Improving Isolation of Extracellular Vesicles by Utilizing Nanomaterials

Zhang, H., Zhang, Q., Deng, Y., Chen, M., & Yang, C.

Membranes · 2022 · Vol. 12(1)

Possible contribution of hepatocyte secretion to the elevation of plasma exosomal arginase-1 in high-fat diet-fed mice

Ogino N, Takahashi H, Nagaoka K, Harada Y, Kubo M, Miyagawa K, Kusanaga M, Oe S, Honma Y, Harada M, Eitoku M, Suganuma N, Ogino K.

 Life Sciences · 2021 · Vol. 278(119588)

Formation and Evaluation of a Two-Phase Polymer System in Human Plasma as a Method for Extracellular Nanovesicle Isolation

Slyusarenko M, Nikiforova N, Sidina E, Nazarova I, Egorov V, Garmay Y, Merdalimova A, Yevlampieva N, Gorin D, Malek A.

Polymers · 2021 · Vol. 13(3)

Stimulation of THP-1 Macrophages with LPS Increased the Production of Osteopontin-Encapsulating Exosome

Bai, G., Matsuba, T., Niki, T., & Hattori, T.

International Journal of Molecular Sciences · 2020 · Vol. 21(22)

Preclinical Characterization and In Vivo Imaging of 111 In-Labeled Mesenchymal Stem Cell–Derived Extracellular Vesicles

Lu CH, Chen YA, Ke CC, Chiu SJ, Chen CC, Hsieh YJ, Yang BH, Liu RS.

Molecular Imaging and Biology · 2020 · Vol. 23(3)

Isolation of extracellular vesicles improves the detection of mutant DNA from plasma of metastatic melanoma patients

Zocco D, Bernardi S, Novelli M, Astrua C, Fava P, Zarovni N, Carpi FM, Bianciardi L, Malavenda O, Quaglino P, Foroni C, Russo D, Chiesi A, Fierro MT.

Scientific Reports · 2020 · Vol. 10(1)

Polymer-Based Precipitation of Extracellular Vesicular microRNAs From Serum Improve Gastric Cancer microRNA Biomarker Performance

Chung, K. Y., Quek, J. M., Neo, S. H., & Too, H. P.

he Journal of Molecular Diagnostics · 2020 · Vol. 22(5)

Isolation and characterization of extracellular vesicles from Broncho-alveolar lavage fluid: a review and comparison of different methods

Carnino, J. M., Lee, H., & Jin, Y.

Respiratory Research · 2019 · Vol. 20(1)

The Regenerative Potential of Amniotic Fluid Stem Cell Extracellular Vesicles: Lessons Learned by Comparing Different Isolation Techniques

Antounians, L., Tzanetakis, A., Pellerito, O., Catania, V. D., Sulistyo, A., Montalva, L., ... & Zani, A.

Scientific Reports · 2019 · Vol. 9(1)

Exosomes from mesenchymal stem cells induce the conversion of hepatocytes into progenitor oval cells

Wu, H. H., & Lee, O. K.

Stem Cell Research & Therapy · 2017 · Vol. 8(1)

Progress in exosome associated tumor markers and their detection methods

Shen M, Di K, He H, Xia Y, Xie H, Huang R, Liu C, Yang M, Zheng S, He N, Li Z.

Molecular Biomedicine · 2020 · Vol. 1(3)

Automated Cryo‐EM and Supervised Machine Learning Enable Reproducible Characterization of Extracellular Vesicles and Co‐Isolating Particles

Enciso‐Martinez, A., Faas, F. G. A., de Jong, A. W. M., van Leeuwen, T. G., Nieuwland, R., van der Pol, E., ten Dijke, P., & Koning, R. I.

Journal of Extracellular Vesicles · 2026 · Vol. 15(4)

Surface‐Associated Proteins on Extracellular Vesicles Remodel the Tumor Microenvironment by Potentiating TGF‐β Signaling in a Contact‐Dependent Manner

Li, C., Enciso‐Martinez, A., Zhu, L., Rotman, S. A., van Veelen, P. A., Koning, R. I., Mei, H., & ten Dijke, P.

Advanced Science · 2025 · Vol. 13(8)

Extracellular vesicles derived from stressed beta cells mediate monocyte activation and contribute to islet inflammation

Dekkers, M. C., Lambooij, J. M., Pu, X., Fagundes, R. R., Enciso-Martinez, A., Kats, K., Giepmans, B. N. G., Guigas, B., & Zaldumbide, A.

Frontiers in Immunology · 2024 · Vol. 15

TGF‐β regulates the release of breast cancer cell‐derived extracellular vesicles and the sorting of their protein cargo by downregulating RAB27B expression

Li, C., Enciso‐Martinez, A., Koning, R. I., Shahsavari, M., & Dijke, P. T.

Journal of Extracellular Vesicles · 2024 · Vol. 13(12)

Amine-Functionalized Gellan Gum-Based Hydrogel Loaded with Adipose Stem Cell-Derived Small Extracellular Vesicles: An In Vitro Proof of Concept for Enhancing Diabetic Foot Ulcer Healing

Tomasello, L., Biondo, M., Biscari, G., Di Rosa, L., Palumbo, F. S., Fiorica, C., Pitarresi, G., Vasto, S., Pizzolanti, G., & Arnaldi, G.

Gels · 2025 · Vol. 11(2)

Targeting HER2 with DNA Aptamers for Efficient Anticancer Drug Delivery: A Combined Experimental and Computational Study

Katsuba, K. E., Zabegina, L. M., Plevako, D. S., Gurtovenko, A. A., & Malek, A. V.

Bioconjugate Chemistry · 2025 · Vol. 36(6)

Immunomodulatory effects of MDA-MB-231-derived exosome mimetic nanovesicles on CD4+ T cell line

Mustafa Oztatlici, Alper Tunga Ozdemir, Hulya Oztatlici, Serife Kucukhuyuk, Rabia Bilge Ozgul Ozdemir, Hilmi Orhan, Kemal Ozbilgin

Eurasian Journal of Medicine and Oncology · 2024 · Vol. 8(1)

Diagnosis of Prostate Cancer through the Multi-Ligand Binding of Prostate-Derived Extracellular Vesicles and miRNA Analysis

Zabegina L, Zyatchin I, Kniazeva M, Shalaev A, Berkut M, Sharoyko V, Mikhailovskii V, Kondratov K, Reva S, Nosov A, Malek A.

Life · 2023 · Vol. 13(4)

In-Vitro Evaluation of Immunomodulation Effects of Mesenchymal Stem Cell-Derived Exosomes in Refractory Chronic Spontaneous Urticaria

Ozdemır AT, Kırmaz C, Ozdemır RBO, Oztatlıcı M, Sonmez PK, Tuglu MI.

Asthma Allergy Immunology · 2023 · Vol. 21

AuNP Aptasensor for Hodgkin Lymphoma Monitoring

Slyusarenko M, Shalaev S, Valitova A, Zabegina L, Nikiforova N, Nazarova I, Rudakovskaya P, Vorobiev M, Lezov A, Filatova L, Yevlampieva N, Gorin D, Krzhivitsky P, Malek A.

Biosensors · 2022 · Vol. 12(1)

MiRNA let-7 from TPO (+) Extracellular Vesicles is a Potential Marker for a Differential Diagnosis of Follicular Thyroid Nodules

Zabegina L, Nazarova I, Knyazeva M, Nikiforova N, Slyusarenko M, Titov S, Vasilyev D, Sleptsov I, Malek A.

Cells · 2020 · Vol. 9(8)

Cryo-electron microscopy of extracellular vesicles from cerebrospinal fluid

Emelyanov A, Shtam T, Kamyshinsky R, Garaeva L, Verlov N, Miliukhina I, Kudrevatykh A, Gavrilov G, Zabrodskaya Y, Pchelina S, Konevega A.

PloS one · 2020 · Vol. 15(1)

Plasma exosomal microRNA‑125b as a monitoring biomarker of resistance to mFOLFOX6‑based chemotherapy in advanced and recurrent colorectal cancer patients

Yagi T, Iinuma H, Hayama T, Matsuda K, Nozawa K, Tsukamoto M, Shimada R, Akahane T, Tsuchiya T, Ozawa T, Hashiguchi Y.

Molecular and Clinical Oncology · 2019 · Vol. 11(4)

Plasma exosomes stimulate breast cancer metastasis through surface interactions and activation of FAK signaling

Shtam T, Naryzhny S, Samsonov R, Karasik D, Mizgirev I, Kopylov A, Petrenko E, Zabrodskaya Y, Kamyshinsky R, Nikitin D, Sorokin M, Buzdin A, Gil-Henn H, Malek A.

 Breast Cancer Research and Treatment · 2019 · Vol. 174(1)

Mesenchymal stromal cell-derived exosome-rich fractionated secretome confers a hepatoprotective effect in liver injury

Damania, A., Jaiman, D., Teotia, A. K., & Kumar, A.

Stem Cell Research & Therapy · 2018 · Vol. 9(1)

Nanoscopic technologies toward molecular profiling of single extracellular vesicles for cancer liquid biopsy

Jalali, M., Lu, Y., del Real Mata, C., Rak, J., & Mahshid, S.

Applied Physics Reviews · 2025 · Vol. 12(1)

Inhibition of miRNA associated with a disease-specific signature and secreted via extracellular vesicles of systemic lupus erythematosus patients suppresses target organ inflammation in a humanized mouse model

Young, N. A., Schwarz, E., Zeno, B. M., Bruckner, S., Mesa, R. A., Jablonski, K., Wu, L., Roberson, E. D. O., & Jarjour, W. N.

Frontiers in Immunology · 2024 · Vol. 14

Novel loading protocol combines highly efficient encapsulation of exogenous therapeutic toxin with preservation of extracellular vesicles properties, uptake and cargo activity

Zuppone, S., Zarovni, N., Noguchi, K., Loria, F., Morasso, C., Lõhmus, A., Nakase, I., & Vago, R.

Discover Nano · 2024 · Vol. 19(1)

Small Extracellular Vesicles (sEVs) Biogenesis Molecular Players Are Associated with Clinical Outcome of Colorectal Cancer Patients

Kottorou A, Dimitrakopoulos FI, Diamantopoulou G, Kalofonou F, Stavropoulos M, Thomopoulos K, Makatsoris T, Koutras A, Kalofonos H.

Cancers · 2023 · Vol. 15(6)

Mladenović, D., Khamari, D., Kittel, Á., Koort, K., Buzás, E. I., & Zarovni, N.

Acidification of blood plasma facilitates the separation and analysis of extracellular vesicles

Journal of Thrombosis and Haemostasis · 2023 · Vol. 21(4)

A Method for Using Cell-Penetrating Peptides for Loading Plasmid DNA into Secreted Extracellular Vesicles

Nebogatova, J., Härk, H. H., Puskar, A., Porosk, L., Guazzi, P., Dowaidar, M., Langel, Ü., & Kurrikoff, K.

Biomolecules · 2023 · Vol. 13(12)

Exosomes Recovered From the Plasma of COVID-19 Patients Expose SARS-CoV-2 Spike-Derived Fragments and Contribute to the Adaptive Immune Response

Pesce E, Manfrini N, Cordiglieri C, Santi S, Bandera A, Gobbini A, Gruarin P, Favalli A, Bombaci M, Cuomo A, Collino F, Cricrì G, Ungaro R, Lombardi A, Mangioni D, Muscatello A, Aliberti S, Blasi F, Gori A, Abrignani S, De Francesco R, Biffo S, Grifantini R.

Frontiers in Immunology · 2022 · Vol. 12(785941)

A proteomic approach to understand the clinical significance of acute myeloid leukemia-derived extracellular vesicles reflecting essential characteristics of leukemia

Kang KW, Kim H, Hur W, Jung JH, Jeong SJ, Shin H, Seo D, Jeong H, Choi B, Hong S, Kim HK, Choi Y, Park JH, Lee KY, Kim KP, Park Y.

Molecular & Cellular Proteomics · 2021 · Vol. 20(100017)

Preclinical Characterization and In Vivo Imaging of 111 In-Labeled Mesenchymal Stem Cell–Derived Extracellular Vesicles

Lu CH, Chen YA, Ke CC, Chiu SJ, Chen CC, Hsieh YJ, Yang BH, Liu RS.

Molecular Imaging and Biology · 2021 · Vol. 23(3)

Cell Derived Extracellular Vesicles: From Isolation, Functionalization towards Biomedical Applications

Lian Zhu, Na Xu, Zhi-Ling Zhang, Tong-Cun Zhang

Biomaterials Science · 2019 · Vol. 7(9)

Multiplexed immunophenotyping of circulating exosomes on nano-engineered ExoProfile chip towards early diagnosis of cancer

Zhang, P., Zhou, X., & Zeng, Y.

Chemical Science · 2019 · Vol. 10(21)

Rapid and label-free isolation of small extracellular vesicles from biofluids utilizing a novel insulator based dielectrophoretic device

Shi, L., Kuhnell, D., Borra, V. J., Langevin, S. M., Nakamura, T., & Esfandiari, L.

Lab on a Chip · 2019 · Vol. 19(21)

Hypoxia preconditioned renal tubular epithelial cell-derived extracellular vesicles alleviate renal ischaemia-reperfusion injury mediated by the HIF-1α/Rab22 pathway and potentially affected by microRNAs

Zhang L, Liu H, Xu K, Ling Z, Huang Y, Hu Q, Lu K, Liu C, Wang Y, Liu N, Zhang X, Xu B, Wu J, Chen S, Zhang G, Chen M.

International Journal of Biological Sciences · 2019 · Vol. 15(6)

Mesenchymal stromal cell-derived exosome-rich fractionated secretome confers a hepatoprotective effect in liver injury

Damania, A., Jaiman, D., Teotia, A. K., & Kumar, A.

Stem Cell Research & Therapy · 2018 · Vol. 9(1)

Inhibition of exosome release by ketotifen enhances sensitivity of cancer cells to doxorubicin

Khan FM, Saleh E, Alawadhi H, Harati R, Zimmermann WH, El-Awady R.

Cancer Biology & Therapy · 2018 · Vol. 19(1)

Development of a Highly Sensitive Device for Counting the Number of Disease-Specific Exosomes in Human Sera

Kabe Y, Suematsu M, Sakamoto S, Hirai M, Koike I, Hishiki T, Matsuda A, Hasegawa Y, Tsujita K, Ono M, Minegishi N, Hozawa A, Murakami Y, Kubo M, Itonaga M, Handa H.

Clinical Chemistry · 2018 · Vol. 64(10)

Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment

Musante, L., Tataruch-Weinert, D., Kerjaschki, D., Henry, M., Meleady, P., & Holthofer, H.

Journal of Extracellular Vesicles · 2017 · Vol. 6(1)

Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction

Foster BP, Balassa T, Benen TD, Dominovic M, Elmadjian GK, Florova V, Fransolet MD, Kestlerova A, Kmiecik G, Kostadinova IA, Kyvelidou C, Meggyes M, Mincheva MN, Moro L, Pastuschek J, Spoldi V, Wandernoth P, Weber M, Toth B, Markert UR.

Critical Reviews in Clinical Laboratory Sciences · 2016 · Vol. 53(6)

Tumour‐derived exosomes: Tiny envelopes for big stories

Miller, I. V., & Grunewald, T. G.

Biology of the Cell · 2015 · Vol. 107(9)

Clinical significance of serum caveolin‐1 levels in melanoma patients

Tas, F., Karabulut, S., Tilgen Yasasever, C., & Duranyildiz, D.

International Journal of Dermatology · 2015 · Vol. 55(5)

Integrated isolation and quantitative analysis of exosome shuttled proteins and nucleic acids using immunocapture approaches

Zarovni N, Corrado A, Guazzi P, Zocco D, Lari E, Radano G, Muhhina J, Fondelli C, Gavrilova J, Chiesi A.

Methods · 2015 · Vol. 87

Exosome release and low pH belong to a framework of resistance of human melanoma cells to cisplatin

Federici C, Petrucci F, Caimi S, Cesolini A, Logozzi M, Borghi M, D'Ilio S, Lugini L, Violante N, Azzarito T, Majorani C, Brambilla D, Fais S.

PloS one · 2014 · Vol. 9(2)

The Development of Stem Cell–Derived Exosomes As a Cell-Free Regenerative Medicine

Vishnubhatla, I., Corteling, R., Stevanato, L., Hicks, C., & Sinden, J.

Journal of Circulating Biomarkers · 2014 · Vol. 143(2)

Isolation and characterization of CD34+ blast-derived exosomes in acute myeloid leukemia

Hong, C. S., Muller, L., Boyiadzis, M., & Whiteside, T. L.

PloS one · 2014 · Vol. 9(8)

Extracellular vesicles as an emerging mechanism of cell-to-cell communication

Tetta, C., Ghigo, E., Silengo, L., Deregibus, M. C., & Camussi, G.

Endocrine · 2013 · Vol. 44(1)

Exosomes: the future of biomarkers in medicine

Properzi, F., Logozzi, M., & Fais, S.

Biomarkers · 2013 · Vol. 7(5)

High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients

Logozzi M, De Milito A, Lugini L, Borghi M, Calabrò L, Spada M, Perdicchio M, Marino ML, Federici C, Iessi E, Brambilla D, Venturi G, Lozupone F, Santinami M, Huber V, Maio M, Rivoltini L, Fais S.

PloS one · 2009 · Vol. 4(4)

In‐Solution Characterization of Extracellular Vesicles: A New Approach to Evaluating Antibody Binding and Surface Interactions

Kakavoulia, M., Spies, P., Kutzner, T. J., Tertel, T., Franzmeier, S., Andaloussi, S. E., Giebel, B., Kaltner, H., Meinel, D., Görgens, A., & Ludwig, A.

Journal of Extracellular Vesicles · 2026 · Vol. 15(4)

Simultaneous Expression of Sigma‐1 Receptor and Tetraspanins Highlights Pathways of Receptor Sorting Into Extracellular Vesicles

Vavers, E., Kopanchuk, S., Veiksina, S., Jonane, J., Mathur, C., Nasirova, N., Midekessa, G., & Rinken, A.

Journal of Neurochemistry · 2026 · Vol. 170(4)

Method Evaluation of Liquid Biopsy Proteomics for Limited Plasma Volume

Takahashi, R., Prodinger, F., & Matsui, A.

Molecular & Cellular Proteomics · 2026 · Vol. 25(6)

Establishing a standard workflow for fluorescence-based nanoparticle tracking analysis for the reliable quantification of extracellular vesicles

Han, Y., Kim, M., Gerelkhuu, Z., Kwon, S. J., Bang, H., Ha, E., & Yoon, T. H.

Methods · 2026 · Vol. 254

Comparison of polyester (PET) capillary-channeled polymer (C-CP) fiber spin-down tips and size exclusion chromatography (SEC) for the isolation of HEK 293-derived extracellular vesicles (EVs)

Mata, C., Topper, C. D., & Marcus, R. K.

Analytical and Bioanalytical Chemistry · 2026

Monitoring HEK293 cell extracellular vesicle (EV) production via a polyester capillary-channeled polymer (C-CP) fiber column with HIC modality

Pons, W. F., Beitle, S., Ewonde, R. E., Harcum, S. W., & Marcus, R. K.

Journal of Chromatography B · 2026 · Vol. 1274(124970)

Elucidation of extracellular vesicles behavior during capillary isoelectric focusing

Zohouri, D., Mai, T. D., Reyre, M., Smadja, C., Krupova, Z., Talbot, L., & Taverna, M.

Talanta · 2025 · Vol. 293(128055)

Limitations and challenges in the characterization of extracellular vesicles from stem cells and serum

Escudero-Cernuda, S., Eiro, N., Fraile, M., Vizoso, F. J., Fernández-Colomer, B., & Fernández-Sánchez, M. L.

Microchimica Acta · 2025 · Vol. 192(5)

Development of a high-sensitivity assay for direct quantitation of EGFr on extracellular vesicles in plasma

Olsen, D. A., Hansen, T. F., Brandslund, I., & Madsen, J. S.

Journal of Immunological Methods · 2025 · Vol. 541(113877)

Comprehensive Comparison of Methods for Isolation of Extracellular Vesicles from Human Plasma

Suresh, P. S., & Zhang, Q.

Journal of Proteome Research · 2025 · Vol. 24(6)

Effects of packing density and adsorption conditions on extracellular vesicle dynamic binding capacities for Capillary-Channeled polymer (C-CP) fiber columns

Islam, M. K. B., & Marcus, R. K.

Journal of Chromatography A · 2025 · Vol. 1755(466068)

Automated Microfluidic Platform for Single Spheroid Culture and Extracellular Vesicle Isolation: Application to Spheroid Transcriptomic Profiling

Hut, M., Denis, J., Bottausci, F., Cubizolles, M., Laurent, P., Kaal, J., Benessalah, M., Boizot, F., Cherradi, N., Fouillet, Y., & Agache, V.

Small · 2025 · Vol. 21(48)

p.N370S GBA1 Mutation Influences the Morphology and Lipid Composition of Extracellular Vesicles in Blood Plasma from Patients with Parkinson’s Disease

Usenko, T. S., Kopytova, A. E., Izyumchenko, A. D., Kulabukhova, D. G., Silantyev, A. S., Kazakova, V. D., Basharova, K. S., Bezrukova, A. I., Garaeva, L. A., Pichkur, E. B., Artynyuk, A. V., Miliukhina, I. V., Timofeeva, A. A., Miroshnikova, V. V., Naryzhny, S. N., Emelyanov, A. K., Zakharzhevskaya, N. B., Konevega, A. L., Shtam, T. A., & Pchelina, S. N.

International Journal of Molecular Sciences · 2025 · Vol. 26(18)

The analytical impact of extracellular vesicles PSA on different commercial total PSA measurement methods

Moreno, A., Sandúa, A., Ferrer-Costa, R., Jacobs-Cacha, C., Varo, N., Ancizu-Marckert, J., Robles, J. E., Pérez Gracia, J. L., Alegre, E., & González, Á.

Biochemia Medica · 2025 · Vol. 36(1)

A New Strategy to Functionalize Exosomes via Enzymatic Engineering of Surface Glycans and its Application to Profile Exosomal Glycans and Endocytosis

Kundu, S., Guo, J., Islam, Md. S., Rohokale, R., Jaiswal, M., & Guo, Z.

Advanced Science · 2025 · Vol. 12(2415942)

Enhanced separation of extracellular vesicles using capillary isotachophoresis with spacer compounds

De Putter, M. P. P., Capuano, A., Numan, M., Hankemeier, T., & Shakalisava, Y.

Electrophoresis · 2025 · Vol. 46

Evaluation of unmodified human cell‐derived extracellular vesicle mitochondrial deoxyribonucleic acid‐based biodistribution in rodents

Cho, Y., Cho, M. Y., Yoon, J., Hong, D. E., Lee, J., Park, H. S., Lee, H., Hong, K. S., Won‐Kyu, L., Saehae, C., Song, S., & Noh, Y.

Journal of Extracellular Vesicles · 2024 · Vol. 13(7)

Intermittent lysis on a single paper-based device to extract exosomal nucleic acid biomarkers from biological samples for downstream analysis

Vu, V., Vu, C., Huang, C., Cheng, C., Pan, S., & Chen, W.

Microchimica Acta · 2024 · Vol. 191(8)

Efficient enzymatic glycan engineering of extracellular vesicles using Nanomaterial-Interfaced microfluidics

Zhou, X., Jaiswal, M., Shi, J., Guo, J., Kundu, S., Guo, Z., & Zeng, Y.

ACS Applied Materials & Interfaces · 2024 · Vol. 17(1)

Increased tube formation and up-regulation of FGFR3 mRNA expression in microvascular endothelial cell by exosomes derived from SW480-7

Ng, C. T., Yip, W. K., Mohtarrudin, N., Jabar, M. F., & Seow, H. F.

Malays J Pathol. · 2023 · Vol. 45(2)

Ultrasensitive and High‐Resolution protein spatially decoding framework for tumor extracellular vesicles

Cheng, C., Hou, K., Hsu, C., & Chiang, L.

Advanced Science · 2023 · Vol. 11(3)

A rapid capillary-channeled polymer (C-CP) fiber spin-down tip approach for the isolation of plant-derived extracellular vesicles (PDEVs) from 20 common fruit and vegetable sources

Jackson, K. K., Mata, C., & Marcus, R. K.

Talanta · 2023 · Vol. 252(123779)

Ultrafast sensitivity-controlled and specific detection of extracellular vesicles using optical force with antibody-modified microparticles in a microflow system

Nanoscale Horizons

Nanoscale Horizons · 2023 · Vol. 8(8)

PSA reactivity in extracellular microvesicles to commercial immunoassays

Sandúa, A., Sanmamed, M. F., Rodríguez, M., Ancizu-Marckert, J., Gúrpide, A., Perez-Gracia, J. L., ... & González, Á.

Clinica Chimica Acta · 2023 · Vol. 543(117303)

Detecting early-stage malignant melanoma using a calcium switch-enriched exosome subpopulation containing tumor markers as a sample

Choi, D. Y., Park, J. N., Paek, S. H., Choi, S. C., & Paek, S. H.

Biosensors and Bioelectronics · 2022 · Vol. 198(113828)

Rapid isolation and quantification of extracellular vesicles from suspension‐adapted human embryonic kidney cells using capillary‐channeled polymer fiber spin‐down tips

Jackson, K. K., & Marcus, R. K.

Electrophoresis · 2022 · Vol. 44(1-2)

A novel approach for enumeration of extracellular vesicles from crude and purified cell culture samples

Kruse, T., Schneider, S., Reger, L. N., Kampmann, M., & Reif, O. W.

Engineering in Life Sciences · 2022 · Vol. 22(3-4)

Fast quantification of extracellular vesicles levels in early breast cancer patients by Single Molecule Detection Array (SiMoA)

Morasso, C., Ricciardi, A., Sproviero, D., Truffi, M., Albasini, S., Piccotti, F., ... & Corsi, F.

Breast cancer research and treatment · 2022 · Vol. 192(1)

Real time imaging of single extracellular vesicle pH regulation in a microfluidic cross-flow filtration platform

Riazanski, V., Mauleon, G., Lucas, K., Walker, S., Zimnicka, A. M., McGrath, J. L., & Nelson, D. J.

Communications biology · 2022 · Vol. 5(1)

Facile, generic capture and on-fiber differentiation of exosomes via confocal immunofluorescence microscopy using a capillary-channeled polymer fiber solid-phase extraction tip

Jackson, K. K., Powell, R. R., Bruce, T. F., & Marcus, R. K.

Sensors & Diagnostics · 2022 · Vol. 1(3)

Multi-target polydiacetylene liposome-based biosensor for improved exosome detection

Kim, C., Han, B. H., Kim, D., Lee, G., Hong, C., Kang, J. Y., & Lee, K.

Sensors and Actuators B: Chemical · 2022 · Vol. 355(131286)

Mouse tissue glycome atlas 2022 highlights inter-organ variation in major N-glycan profiles

Otaki, M., Hirane, N., Natsume-Kitatani, Y., Nogami Itoh, M., Shindo, M., Kurebayashi, Y., & Nishimura, S. I.

Scientific reports · 2022 · Vol. 12(1)

Determination of the Loading Capacity and Recovery of Extracellular Vesicles Derived from Human Embryonic Kidney Cells and Urine Matrices on Capillary-Channeled Polymer (C-CP) Fiber Columns

Billotto, L. S., Jackson, K. K., & Marcus, R. K.

Separations · 2022 · Vol. 9(9)

Urine stabilization and normalization strategies favor unbiased analysis of urinary EV content

Vago, R., Radano, G., Zocco, D., & Zarovni, N.

Scientific Reports · 2022 · Vol. 12(1)

Quantification and Phenotypic Characterization of Extracellular Vesicles from Patients with Acute Myeloid and B-Cell Lymphoblastic Leukemia

Miljkovic-Licina, M., Arraud, N., Zahra, A. D., Ropraz, P., & Matthes, T.

Cancers · 2022 · Vol. 14(1)

Calibration-free analysis of surface proteins on single extracellular vesicles enabled by DNA nanostructure

Guo, K., Li, Z., Win, A., Coreas, R., Adkins, G. B., Cui, X., ... & Zhong, W.

Biosensors and Bioelectronics · 2021 · Vol. 192(113502)

A sandwich-based evanescent wave fluorescent biosensor for simple, real-time exosome detection

Li, S., Zhu, L., Zhu, L., Mei, X., & Xu, W.

Biosensors and Bioelectronics · 2021 · Vol. 200(113902)

AL-PHA beads: Bioplastic-based protease biosensors for global health applications

Richard J.R. Kelwick, Alexander J. Webb, Yizhou Wang, Amelie Heliot, Fiona Allan, Aidan M. Emery, Michael R. Templeton, Paul S. Freemont

Materials Today · 2021 · Vol. 47

A simple method for the analysis of extracellular vesicles enriched for exosomes from human serum by capillary electrophoresis with ultraviolet diode array detection

El Ouahabi, O., Salim, H., Pero-Gascon, R., & Benavente, F.

Journal of Chromatography A · 2021 · Vol. 1635(461752)

A novel assay for exosomal and cell-free miRNA isolation and quantification

Grunt, M., Failla, A. V., Stevic, I., Hillebrand, T., & Schwarzenbach, H.

RNA Biology · 2020 · Vol. 17(4)

Differential fluorescence nanoparticle tracking analysis for enumeration of the extracellular vesicle content in mixed particulate solutions

Desgeorges, A., Hollerweger, J., Lassacher, T., Rohde, E., Helmbrecht, C., & Gimona, M.

Methods · 2020 · Vol. 177

Systematic Evaluation of PKH Labelling on Extracellular Vesicle Size by Nanoparticle Tracking Analysis

Dehghani, M., Gulvin, S. M., Flax, J., & Gaborski, T. R.

Scientific Reports · 2020 · Vol. 10(1)

Paper-Based Preconcentration and Isolation of Microvesicles and Exosomes

Lee, D., Wee, K. W., Kim, H., Han, S. I., Kwak, S., Yoon, D. S., & Lee, J. H.

Journal of Visualized Experiments (JoVE) · 2020 · Vol. 158

Comprehensive Molecular Profiles of Functionally Effective MSC-Derived Extracellular Vesicles in Immunomodulation

Kim, H., Lee, M. J., Bae, E. H., Ryu, J. S., Kaur, G., Kim, H. J., ... & Shigemoto-Kuroda, T.

Molecular Therapy · 2020 · Vol. 28(7)

Nanoparticle-based biosensors for detection of extracellular vesicles in liquid biopsies

Martin-Gracia, B., Martin-Barreiro, A., Cuestas-Ayllon, C., Grazu, V., Line, A., Llorente, A., ... & Moros, M.

Journal of Materials Chemistry B. · 2020 · Vol. 8(31)

Fast and Purification-Free Characterization of Bio-Nanoparticles in Biological Media by Electrical Asymmetrical Flow Field-Flow Fractionation Hyphenated with Multi-Angle Light Scattering and Nanoparticle Tracking Analysis Detection

Drexel, R., Siupa, A., Carnell-Morris, P., Carboni, M., Sullivan, J., & Meier, F.

Molecules · 2020 · Vol. 25(20)

Exosomal microRNAs Release as a Sensitive Marker for Drug-Induced Liver Injury In Vitro

Messner, C. J., Premand, C., Gaiser, C., Kluser, T., Kübler, E., & Suter-Dick, L.

 Applied In Vitro Toxicology · 2020 · Vol. 6(3)

Enhanced paper-based ELISA for simultaneous EVs/exosome isolation and detection using streptavidin agarose-based immobilization

Lee, J., Kim, H., Heo, Y., Yoo, Y. K., Han, S. I., Kim, C., ... & Lee, J. H.

Analyst · 2020 · Vol. 145(1)

Paper-based ITP technology: An application to specific cancer-derived exosome detection and analysis

Guo, S., Xu, J., Estell, A. P., Ivory, C. F., Du, D., Lin, Y., & Dong, W. J.

Biosensors and Bioelectronics · 2020 · Vol. 164(112292)

Analysis of Neat Biofluids Obtained During Cardiac Surgery Using Nanoparticle Tracking Analysis: Methodological Considerations

Shearn, A. I., Aday, S., Ben-Aicha, S., Carnell-Morris, P., Siupa, A., Angelini, G. D., ... & Biglino, G

Frontiers in Cell and Developmental Biology · 2020 · Vol. 8(367)

Use of nanosphere self-assembly to pattern nanoporous membranes for the study of extracellular vesicles

Mireles, M., Soule, C., Dehghani, M., & Gaborski, T. R.

Nanoscale Advances · 2020 · Vol. 2(10)

Extracellular vesicle-mediated nucleic acid transfer and reprogramming in the tumor microenvironment

Parayath, N. N., Padmakumar, S., & Amiji, M. M.

Cancer Letters · 2020 · Vol. 482

Carbon-Coated Superparamagnetic Nanoflowers for Biosensors Based on Lateral Flow Immunoassays

Moyano, A., Serrano-Pertierra, E., Salvador, M., Martínez-García, J. C., Piñeiro, Y., Yañez-Vilar, S., ... & Blanco-López, M. C.

Biosensors · 2020 · Vol. 10(8)

Plasma extracellular vesicles detected by Single Molecule array technology as a liquid biopsy for colorectal cancer

Wei, P., Wu, F., Kang, B., Sun, X., Heskia, F., Pachot, A., ... & Li, D.

Journal of Extracellular Vesicles · 2020 · Vol. 9(1)

Detection of Salivary Small Extracellular Vesicles Associated Inflammatory Cytokines Gene Methylation in Gingivitis

Han, P., Lai, A., Salomon, C., & Ivanovski, S.

International Journal of Molecular Sciences · 2020 · Vol. 21(15)

AFM-based high-throughput nanomechanical screening of single extracellular vesicles

Ridolfi, A., Brucale, M., Montis, C., Caselli, L., Paolini, L., Borup, A., ... & Nejsum, P.

Analytical chemistry · 2020 · Vol. 92(15)

Isolation and quantification of human urinary exosomes by hydrophobic interaction chromatography on a polyester capillary-channeled polymer fiber stationary phase

Huang, S., Wang, L., Bruce, T. F., & Marcus, R. K.

Analytical and bioanalytical chemistry · 2019 · Vol. 411(25)

Profiling surface proteins on individual exosomes using a proximity barcoding assay

Wu, D., Yan, J., Shen, X., Sun, Y., Thulin, M., Cai, Y., ... & Kamali-Moghaddam, M.

Nature Communications · 2019 · Vol. 10(1)

High sensitivity detection of extracellular vesicles immune-captured from urine by conventional flow cytometry

Campos-Silva, C., Suárez, H., Jara-Acevedo, R., Linares-Espinós, E., Martinez-Piñeiro, L., Yáñez-Mó, M., & Valés-Gómez, M.

Scientific Reports · 2019 · Vol. 9(1)

Extracellular Vesicles from Fresh and Dried Plants—Simultaneous Purification and Visualization Using Gel Electrophoresis

Woith, E., & Melzig, M. F.

International Journal of Molecular Sciences · 2019 · Vol. 20(2)

Microfluidic exponential rolling circle amplification for sensitive microRNA detection directly from biological samples

Cao, H., Zhou, X., & Zeng, Y.

ensors and Actuators B: Chemical · 2019 · Vol. 279

Clinical impact of different exosomes’ protein expression in pancreatic ductal carcinoma patients treated with standard first line palliative chemotherapy

Giampieri, R., Piva, F., Occhipinti, G., Bittoni, A., Righetti, A., Pagliaretta, S., ... & Ricci, G.

PloS one · 2019 · Vol. 14(5)

Label-free Exosomal Detection Based on a Low-cost Plasmonic Biosensor Array Integrated with Microfluidics

Lv, X., Geng, Z., Su, Y., Fan, Z., Wang, S., Fang, W., & Chen, H.

Langmuir · 2019 · Vol. 35(30)

Origami-paper-based device for microvesicle/exosome preconcentration and isolation

Kim, H., Lee, K. H., Han, S. I., Lee, D., Chung, S., Lee, D., & Lee, J. H.

Lab on a Chip · 2019 · Vol. 19(23)

Exosome Aggregation Mediated Stop‐Flow Paper‐Based Portable Device for Rapid Exosome Quantification

Chutvirasakul, B., Nuchtavorn, N., Suntornsuk, L., & Zeng, Y.

Electrophoresis · 2019 · Vol. 41(5-6)

Viscosity of Plasma as a Key Factor in Assessment of Extracellular Vesicles by Light Scattering

Božič, D., Sitar, S., Junkar, I., Štukelj, R., Pajnič, M., Žagar, E., ... & Kogej, K.

Cells · 2019 · Vol. 8(9)

Measuring zinc in biological nanovesicles by multiple analytical approaches

Francesco Piacenza, Antje Biesemeier, Marco Farina, Francesco Piva, Xin Jin, Eleonora Pavoni, Lorenzo Nisi, Maurizio Cardelli, Laura Costarelli, Robertina Giacconi, Andrea Basso, Elisa Pierpaoli, Mauro Provinciali, James C.M. Hwang, Antonio Morini, Andrea di Donato, Marco Malavolta

Journal of Trace Elements in Medicine and Biology · 2018 · Vol. 48

Development of a Highly Sensitive Device for Counting the Number of Disease-Specific Exosomes in Human Sera

Kabe Y, Suematsu M, Sakamoto S, Hirai M, Koike I, Hishiki T, Matsuda A, Hasegawa Y, Tsujita K, Ono M, Minegishi N, Hozawa A, Murakami Y, Kubo M, Itonaga M, Handa H.

Clinical Chemistry · 2018 · Vol. 64(10)

Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats

Ohara, M., Ohnishi, S., Hosono, H., Yamamoto, K., Yuyama, K., Nakamura, H., ... & Sakamoto, N.

Stem Cells International · 2018

PKH26 labeling of extracellular vesicles: characterization and cellular internalization of contaminating PKH26 nanoparticles

Dominkuš, P. P., Stenovec, M., Sitar, S., Lasič, E., Zorec, R., Plemenitaš, A., Žagar, E., Kreft, A., & Lenassi, M.

Biochimica et Biophysica Acta (BBA) - Biomembranes · 2018 · Vol. 1860(6)

A low voltage nanopipette dielectrophoretic device for rapid entrapment of nanoparticles and exosomes extracted from plasma of healthy donors

Shi, L., Rana, A., & Esfandiari, L.

Scientific Reports · 2018 · Vol. 8(6751)

Human Cytomegalovirus Reactivation from Latency: Validation of a “Switch” Model In Vitro

Arcangeletti MC, Vasile Simone R, Rodighiero I, De Conto F, Medici MC, Maccari C, Chezzi C, Calderaro A.

Virology Journal · 2016 · Vol. 13(1)

Ultrasensitive Microfluidic Analysis of Circulating Exosomes Using Nanostructured Graphene Oxide/Polydopamine Coating

Peng Zhang, Mei He, Yong Zeng

Lab on a Chip · 2016 · Vol. 16(16)

Development of a rapid lateral flow immunoassay test for detection of exosomes previously enriched from cell culture medium and body fluids

Oliveira-Rodríguez M, López-Cobo S, Reyburn HT, Costa-García A, López-Martín S, Yáñez-Mó M, Cernuda-Morollón E, Paschen A, Valés-Gómez M, Blanco-López MC

Journal of Extracellular Vesicles · 2016 · Vol. 5(31803)

Biological reference materials for extracellular vesicle studies

Valkonen S, van der Pol E, Böing A, Yuana Y, Yliperttula M, Nieuwland R, Laitinen S, Siljander PR

European Journal of Pharmaceutical Sciences · 2016 · Vol. 98

Size Characterization and Quantification of Exosomes by Asymmetrical-Flow Field-Flow Fractionation

Sitar, S., Kejžar, A., Pahovnik, D., Kogej, K., Tušek-Žnidarič, M., Lenassi, M., & Žagar, E.

Analytical Chemistry · 2015 · Vol. 87(18)

Adipocyte-derived exosomal miRNAs: a novel mechanism for obesity-related disease

Ferrante, S. C., Nadler, E. P., Pillai, D. K., Hubal, M. J., Wang, Z., Wang, J. M., ... & Freishtat, R. J.

Pediatric Research · 2014 · Vol. 77(3)

Measurement of Refractive Index by Nanoparticle Tracking Analysis Reveals Heterogeneity in Extracellular Vesicles

Gardiner, C., Shaw, M., Hole, P., Smith, J., Tannetta, D., Redman, C. W., & Sargent, I. L.

Journal of Extracellular Vesicles · 2014 · Vol. 3

Comparison of Methods for the Isolation of Salivary Extracellular Vesicles

Kegler, U., Buhmann, A., Friedl, H.-P., Hofner, M., & Noehammer, C.

International Journal of Molecular Sciences · 2026 · Vol. 27(11)

Perilipin 2 modulates adipogenic differentiation of primary dermal fibroblasts and is extracellularly released during adipocyte maturation

Conte, M., Trofarello, L., Chiariello, A., Storci, G., Tieri, P., Conte, G., Cortini, M., Avnet, S., Baldini, N., Pasquinelli, G., Valente, S., & Salvioli, S.

Cellular and Molecular Life Sciences · 2026

Proteomics Profiling of Neuron-Derived Small Extracellular Vesicles from Human Plasma: Enabling Single-Subject Analysis

Anastasi F, Masciandaro SM, Carratore RD, Dell'Anno MT, Signore G, Falleni A, McDonnell LA, Bongioanni P

International Journal of Molecular Sciences · 2021 · Vol. 22(6)

Isolation of extracellular vesicles improves the detection of mutant DNA from plasma of metastatic melanoma patients

Zocco D, Bernardi S, Novelli M, Astrua C, Fava P, Zarovni N, Carpi FM, Bianciardi L, Malavenda O, Quaglino P, Foroni C, Russo D, Chiesi A, Fierro MT

Scientific Reports · 2020 · Vol. 10(1)

Putative role of circulating Human Papillomavirus DNA in the development of primary squamous cell carcinoma of the middle rectum: a case report

Ambrosio MR, Vernillo R, De Carolis S, Carducci A, Mundo L, Ginori A, Rocca BJ, Nardone V, Lucenti Fei A, Carfagno T, Lazzi S, Cricca M, Tosi P

Frontiers in Oncology · 2019 · Vol. 9(93)

Clues to Non-Invasive Implantation Window Monitoring: Isolation and Characterisation of Endometrial Exosome

Luddi A, Zarovni N, Maltinti E, Governini L, Leo V, Cappelli V, Quintero L, Paccagnini E, Loria F, Piomboni P

Cells · 2019 · Vol. 8(8)

Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians

Storci G, De Carolis S, Papi A, Bacalini MG, Gensous N, Marasco E, Tesei A, Fabbri F, Arienti C, Zanoni M, Sarnelli A, Santi S, Olivieri F, Mensà E, Latini S, Ferracin M, Salvioli S, Garagnani P, Franceschi C, Bonafè M

Cell Death & Differentiation · 2019 · Vol. 26(9)

Integrated isolation and quantitative analysis of exosome shuttled proteins and nucleic acids using immunocapture approaches

Zarovni N, Corrado A, Guazzi P, Zocco D, Lari E, Radano G, Muhhina J, Fondelli C, Gavrilova J, Chiesi A.

Methods · 2015 · Vol. 87

Emerging technologies in extracellular vesicle-based molecular diagnostics

Jia S, Zocco D, Samuels ML, Chou MF, Chammas R, Skog J, Zarovni N, Momen-Heravi F, Kuo WP

Expert review of molecular diagnostics · 2014 · Vol. 14(3)

Menstrual cycle-dependent expression of tRNA-derived fragments in healthy human endometrium and uterine fluid-derived extracellular vesicles

Apostolov, A., Naydenov, M., Kambareva, K., Pathare, A. D. S., Saare, M., Sola-Leyva, A., Salumets, A., Baev, V., & Yahubyan, G.

BMC Genomics · 2026 · Vol. 27(1)

Protein corona modulates extracellular-vesicle recognition at glycan-based nanobiointerfaces

Bertok, T., Jane, E., Solovicova, V., Gajdosova, V. P., Furdova, A., Micusik, M., Sramkova, M., Kozics, K., & Tkac, J.

Biophysical Reports · 2026 · Vol. 6(3)

Bovine oviductal and uterine extracellular vesicles enhance blastocyst development in confined individual embryo culture

Travaglione, A., De Gregorio, V., Candela, A., Genovese, V., Cimmino, M., Cañón-Beltrán, K., Cajas, Y. N., Iniesta-Cuerda, M., Soler, A. J., Rizos, D., Talevi, R., & Gualtieri, R.

Journal of Assisted Reproduction and Genetics · 2026 · Vol. 43(6)

Optimization of isolation and characterization methods for extracellular vesicles from Cucumis sativus apoplast

Devi, N., Devi, N., Gupta, R., Dhir, S., & Walia, Y.

Plant Biotechnology Reports · 2026 · Vol. 20(3)

Extracellular vesicles from small-follicle follicular fluid improve redox balance and embryo development in naturally heat-stressed bovine oocytes

Diaz-Muñoz, J., Flores, E., Cañón-Beltrán, K., Cajas, Y. N., Gago, S., López-Béjar, M., Rizos, D., & Mogas, T.

Theriogenology · 2026 · Vol. 264(118041)

L26/P-091 Seminal exosomal LCN2 levels may be a noninvasive negative predictor for sperm retrieval in infertile men with non-obstructive azoospermia

Cheng, Y., Liu, C. M., Chen, H. Y., Hou, H. C., Lin, T. Y., & Lin, S. C.

Human Reproduction · 2026 · Vol. 41

Molecular Profiling of Extracellular Vesicles Isolated from Boar Reproductive Fluids

Kraus, V., Doleckova, B., Frolikova, M., Sanovec, O., Spevakova, D., Pilsova, Z., Pilsova, A., Komrskova, K., Simonik, O., & Postlerova, P.

Journal of Extracellular Vesicles · 2026 · Vol. 15(7)

Menstrual cycle-dependent expression of tRNA-derived fragments in healthy human endometrium and uterine fluid-derived extracellular vesicles

Apostolov, A., Naydenov, M., Kambareva, K., Pathare, A. D. S., Saare, M., Sola-Leyva, A., Salumets, A., Baev, V., & Yahubyan, G.

BMC Genomics · 2026 · Vol. 27(1)

Multi-omics analysis of uterine fluid extracellular vesicles reveals a resemblance with endometrial tissue across the menstrual cycle: biological and translational insights

Apostolov A., Mladenović, D., Tilk, K., Lõhmus, A., Vesselin Baev, Yahubyan, G., Sola-Leyva, A., Bergamelli, M., André Görgens, Zhao, C., Samir E L Andaloussi, Aive Kalinina, Acharya, G., Lanner, F., Merli Saare, Peters, M., Piomboni, P., Luddi, A., Salumets, A., & Aleksejeva, E.

Human Reproduction Open · 2025 · Vol. 2025(2)

Deciphering the dialogue between the bovine blastocyst and the uterus: embryo-induced alterations in extracellular vesicle protein content from an ex vivo model and the in vivo environment

Mazzarella, R., José María Sánchez, Egido, S. G., McDonald, M., Álvarez-Barrientos, A., González, E., Falcón-Pérez, J. M., Azkargorta, M., Félix Elortza, González, M. E., Lonergan, P., Rizos, D., & Fernandez-Fuertes, B.

Journal of Animal Science and Biotechnology/Journal of Animal Science and Biotechnology · 2025 · Vol. 16(1)

Enhancing developmental potential of vitrified in vitro matured bovine oocytes using extracellular vesicles from large follicles

Diaz-Muñoz, J., Cañón-Beltrán, K., Cajas, Y. N., Gago, S., María Iniesta-Cuerda, Soler, A. J., Rizos, D., & Mogas, T.

Scientific Reports · 2025 · Vol. 15(1)

Microfluidic Production of Exosome-Mimicking Lipid Nanoparticles for Enhanced RNA Delivery: Role of Exosomal Proteins

Masatoshi Maeki, Niwa, A., Oyama, S., Aratani, K., Ito, R., Suzuki, Y., Sato, Y., Ishida, A., Hideyoshi Harashima, & Tokeshi, M.

ACS Applied Materials & Interfaces · 2025 · Vol. 17(29)

Immune evasion through mitochondrial transfer in the tumour microenvironment

Ikeda, H., Kawase, K., Nishi, T., Watanabe, T., Takenaga, K., Inozume, T., Ishino, T., Aki, S., Lin, J., Kawashima, S., Nagasaki, J., Ueda, Y., Suzuki, S., Makinoshima, H., Itami, M., Nakamura, Y., Tatsumi, Y., Suenaga, Y., Morinaga, T., . . . Togashi, Y.

Nature · 2025 · Vol. 638

Human mesenchymal stroma/stem-like cell-derived taxol-loaded EVs/exosomes transfer anti-tumor microRNA signatures and express enhanced SDF-1-mediated tumor tropism

Hass, R., Von Der Ohe, J., & Luo, T.

Cell Communication and Signaling · 2024 · Vol. 22(1)

Scalable production of siRNA‐encapsulated extracellular vesicles for the inhibition of KRAS‐mutant cancer using acoustic shock waves

Kim, H. K., Choi, Y., Kim, K. H., Byun, Y., Kim, T. H., Kim, J. H., An, S. H., Bae, D., Choi, M. K., Lee, M., Kang, G., Chung, J., Kim, S., & Kwon, K.

Journal of Extracellular Vesicles · 2024 · Vol. 13(9)

Goat milk extracellular vesicles: Separation comparison of natural carriers for theragnostic application

Santoro, J., Nuzzo, S., Franzese, M., Salvatore, M., & Grimaldi, A. M.

Heliyon · 2024 · Vol. 10(6)

Oviductal extracellular vesicles miRNA cargo varies in response to embryos and their quality

Hamdi, M., Sánchez, J. M., Fernandez-Fuertes, B., Câmara, D. R., Bollwein, H., Rizos, D., Bauersachs, S., & Almiñana, C.

BMC Genomics · 2024 · Vol. 25(1)

Proteomic profiling of human plasma extracellular vesicles identifies PF4 and C1R as novel biomarker in sarcopenia

Aparicio, P., Navarrete‐Villanueva, D., Gómez‐Cabello, A., López‐Royo, T., Santamaría, E., Fernández‐Irigoyen, J., Ausín, K., Arruebo, M., Sebastian, V., Vicente‐Rodríguez, G., Osta, R., & Manzano, R.

Journal of Cachexia Sarcopenia and Muscle · 2024 · Vol. 15(5)

Immunoaffinity-enriched salivary small extracellular vesicles in periodontitis

Liu, C., Seneviratne, C. J., Palma, C., Rice, G., Salomon, C., Khanabdali, R., Ivanovski, S., & Han, P.

Extracellular Vesicles and Circulating Nucleic Acids · 2023 · Vol. 4(4)

Identification of Novel Senescent Markers in Small Extracellular Vesicles

Misawa T, Hitomi K, Miyata K, Tanaka Y, Fujii R, Chiba M, Loo TM, Hanyu A, Kawasaki H, Kato H, Maezawa Y, Yokote K, Nakamura AJ, Ueda K, Yaegashi N, Takahashi A.

International Journal of Molecular Sciences · 2023 · Vol. 24(3)

Effect of extracellular vesicles derived from hypoxia-preconditioned human mesenchymal stem cells on osteoblastogenesis and adipogenesis in vitro

Casado-Díaz, A., Jiménez-Navarro, C., Torrecillas-Baena, B., Camacho-Cardenosa, M., Quesada-Gómez, J. M., & Gálvez-Moreno, M. Á.

Revista De Osteoporosis Y Metabolismo Mineral · 2023 · Vol. 15(2)

Characterization and identification of extracellular vesicles-coupled miRNA profiles in seminal plasma of fertile and subfertile rabbit bucks

Sakr, O. G., Gad, A., Cañón-Beltrán, K., Cajas, Y. N., Prochazka, R., Rizos, D., & Rebollar, P. G.

Theriogenology · 2023 · Vol. 209

Metabolomics of small extracellular vesicles derived from isocitrate dehydrogenase 1-mutant HCT116 cells collected by semi-automated size exclusion chromatography

Hayasaka, R., Tabata, S., Hasebe, M., Ikeda, S., Hikita, T., Oneyama, C., Yoshitake, J., Onoshima, D., Takahashi, K., Shibata, T., Uchida, K., Baba, Y., Soga, T., Tomita, M., & Hirayama, A.

Frontiers in Molecular Biosciences · 2023 · Vol. 9(1049402)

Targeting YAP1 ameliorates progesterone resistance in endometriosis

Lin, S. C., Li, W. N., Lin, S. C., Hou, H. T., Tsai, Y. C., Lin, T. C., ... & Tsai, S. J.

Human Reproduction · 2023 · Vol. 38(6)

A Method for Using Cell-Penetrating Peptides for Loading Plasmid DNA into Secreted Extracellular Vesicles

Nebogatova, J., Härk, H. H., Puskar, A., Porosk, L., Guazzi, P., Dowaidar, M., Langel, Ü., & Kurrikoff, K.

Biomolecules · 2023 · Vol. 13(12)

Extracellular vesicles from oviductal and uterine fluids supplementation in sequential in vitro culture improves bovine embryo quality

Leal CLV, Cañón-Beltrán K, Cajas YN, Hamdi M, Yaryes A, Millán de la Blanca MG, Beltrán-Breña P, Mazzarella R, da Silveira JC, Gutiérrez-Adán A, González EM, Rizos D.

Journal of Animal Science and Biotechnology · 2022 · Vol. 13(1)

Serum extracellular vesicles profiling is associated with COVID‐19 progression and immune responses

Yim, K. H. W., Borgoni, S., & Chahwan, R.

Journal of Extracellular Biology · 2022 · Vol. 1(4)

Dysregulated HIC1 and RassF1A expression in vitro alters the cell cytoskeleton and exosomal Piwi-interacting RNA

Sun, C. Y., Chen, G. D., He, B. C., Fu, W. E., Lee, C. H., Leu, Y. W., & Hsiao, S. H.

Biochemical and Biophysical Research Communications · 2022 · Vol. 594

Extracellular Vesicles Derived from Primed Mesenchymal Stromal Cells Loaded on Biphasic Calcium Phosphate Biomaterial Exhibit Enhanced Macrophage Polarization

Rana, N., Suliman, S., Al-Sharabi, N., & Mustafa, K.

Cells · 2022 · Vol. 11(3)

The emerging role of small extracellular vesicles in saliva and gingival crevicular fluid as diagnostics for periodontitis

Han, P., Bartold, P. M., & Ivanovski, S.

Journal of Periodontal Research · 2022 · Vol. 57(1)

CM-Dil Staining and SEC of Plasma as an Approach to Increase Sensitivity of Extracellular Nanovesicles Quantification by Bead-Assisted Flow Cytometry

Nikiforova, N., Chumachenko, M., Nazarova, I., Zabegina, L., Slyusarenko, M., Sidina, E., & Malek, A.

Membranes · 2021 · Vol. 11(7)

36 Analysis of miRNA content of oviduct and uterine extracellular vesicles across the bovine estrous cycle

Hamdi, Meriem & Mazzarella, Rosane & Cañón-Beltrán, Karina & Cajas, Yulia N & Leal, Cláudia & Gutiérrez-Adán, Alfonso & González, M. & Coelho da Silveira, Juliano & Rizos, Dimitrios.

Reproduction, Fertility and Development · 2021 · Vol. 33(125)

Isolation, Characterization, and MicroRNA Analysis of Extracellular Vesicles from Bovine Oviduct and Uterine Fluids

Cañón-Beltrán K, Hamdi M, Mazzarella R, Cajas YN, Leal CLV, Gutiérrez-Adán A, González EM, da Silveira JC, Rizos D.

Methods in Molecular Biology · 2021

Coupling size exclusion chromatography to ultracentrifugation improves detection of exosomal proteins from human plasma by LC-MS

Alameldin, S., Costina, V., Abdel-Baset, H. A., Nitschke, K., Nuhn, P., Neumaier, M., & Hedtke, M.

Practical Laboratory Medicine · 2021

Salivary Outer Membrane Vesicles and DNA Methylation of Small Extracellular Vesicles as Biomarkers for Periodontal Status: A Pilot Study

Han, P., Bartold, P. M., Salomon, C., & Ivanovski, S.

Journal of Molecular Sciences · 2021 · Vol. 22(5)

Salivary Small Extracellular Vesicles Associated miRNAs in Periodontal Status—A Pilot Study

Han P, Bartold PM, Salomon C, Ivanovski S.

International Journal of Molecular Sciences · 2020 · Vol. 21(8)

Progress, opportunity, and perspective on exosome isolation-efforts for efficient exosome-based theranostics

Theranostics · 2020 · Vol. 10(8)

76 Extracellular vesicles from oviduct and uterus in sequential culture improve the quality of bovine embryos produced in vitro

Leal C, Cañon-Beltrán K, Cajas Y, Gallego P, Beltrán-Breña P, Hamdi M, González M, Rizos D.

Reproduction, Fertility and Development · 2019 · Vol. 32(164)

Anti-fibrotic effect of Spirulina maxima-derived extracellular vesicles: possible role of PARK7 and HSP70 chaperones

Szebeni, B., Bernáth, M., Bokrossy, P., Pap, D., Molnár, Z., Mészáros, T., Lenzinger, D., Visnovitz, T., Pálmai, M., Mihály, J., Varga, Z., Fekete, N., Pállinger, É., Veres-Székely, A., Szász, C., Buzás, E., Szabó, A. J., & Vannay, Á.

Frontiers in Bioengineering and Biotechnology · 2026

Single-molecule localization microscopy imaging of extracellular vesicle DNA in recipient cells

Zhu, X., Chetty, V. K., Ghanam, J., Hila, A., Yang, Q., Strickfaden, H., Bonn, M., Cremer, C., Hoyer, P. F., Liu, X., & Thakur, B. K.

Journal of Translational Medicine · 2026 · Vol. 24(1)

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Preußer, C., Salander, D. J., Szymanski, W., Graumann, J., Wang, Y., Zhao, K., Bartsch, J. W., Gómez‐Serrano, M., Bachurski, D., Reinartz, S., & von Pogge von Strandmann, E.

Advanced Healthcare Materials · 2026 · Vol. 15(13)

Physical activity-associated extracellular vesicles inhibit inflammagen-induced microglial activation

Su, C.-Y., Hsu, H.-J., Wang, T.-F., Chou, H.-L., Tsai, S.-F., Lee, C.-W., Cheng, C.-L., Wang, Y.-K., & Kuo, Y.-M.

Brain, Behavior, & Immunity - Health · 2026 · Vol. 53

Automated Cryo‐EM and Supervised Machine Learning Enable Reproducible Characterization of Extracellular Vesicles and Co‐Isolating Particles

Enciso‐Martinez, A., Faas, F. G. A., de Jong, A. W. M., van Leeuwen, T. G., Nieuwland, R., van der Pol, E., ten Dijke, P., & Koning, R. I.

Journal of Extracellular Vesicles · 2026 · Vol. 15(4)

Microparticle-Embedded Stem Cell Spheroid Composite Enables High-Yield, Effective, and Homogeneous Production of Extracellular Vesicles

Park, H., Baek, I., Kim, M., Cho, W. J., Jung, H.-D., Kim, Y., Cha, K.-Y., Kim, J., Arai, Y., & Lee, S.-H.

Advanced Composites and Hybrid Materials · 2026 · Vol. 9(4)

MSC-derived extracellular vesicles accelerate wound healing in senescent fibroblast cultures

Rudnitsky, E., Vineshtock, N., Yakubov, N., Braiman, A., Segev, Y., Wolfson, M., Muradian, K. K., Gorbunova, V., Turgeman, G., Shahar, M. B., & Fraifeld, V. E.

Biogerontology · 2026 · Vol. 27(4)

Combinational CSF1R/PD-L1 targeting by BM-MSC-derived exosome–liposome hybrid orchestrates tumor-associated macrophage phagocytosis in an in vitro tumor-microenvironment-dependent manner

Asad Pour, O., Opazo, F., Rostamzadeh, J., Ghanam, J., Chetty, V. K., Hila, A., Neumann, U., Hetze, S., Barthel, L., Best, J., Schmidt, H. H., & Thakur, B. K.

Cancer Nanotechnology · 2026 · Vol. 17(1)

Protein corona modulates extracellular-vesicle recognition at glycan-based nanobiointerfaces

Bertok, T., Jane, E., Solovicova, V., Gajdosova, V. P., Furdova, A., Micusik, M., Sramkova, M., Kozics, K., & Tkac, J.

Biophysical Reports · 2026 · Vol. 6(3)

Isolation and Functional Characterization of Carob-Derived Nanovesicles Reveals Anti-Inflammatory and Regenerative Potential

Manzaneque-López, M. C., Sánchez-López, C. M., Marcilla, A., Pérez-Bermúdez, P., & Soler, C.

Plants · 2026 · Vol. 15(4)

Amine-Functionalized Gellan Gum-Based Hydrogel Loaded with Adipose Stem Cell-Derived Small Extracellular Vesicles: An In Vitro Proof of Concept for Enhancing Diabetic Foot Ulcer Healing

Tomasello, L., Biondo, M., Biscari, G., Di Rosa, L., Palumbo, F. S., Fiorica, C., Pitarresi, G., Vasto, S., Pizzolanti, G., & Arnaldi, G.

Gels · 2025 · Vol. 11(2)

Enolase and 16.5‐kDa Tegument‐Associated Protein in Fasciola hepatica Extracellular Vesicles: Clues to Their Role in Pathogenesis

González-Arce A, Sánchez-López CM, Sánchez-Palencia LF, Marcilla A, Bernal D.

Journal of Extracellular Biology · 2025 · Vol. 4(6)

Enhanced Anti-Tumor Effects of Natural Killer Cell-Derived Exosomes Through Doxorubicin Delivery to Hepatocellular Carcinoma Cells: Cytotoxicity and Apoptosis Study

Choi, Y. H., Kim, H. Y., Park, J.-O., & Choi, E.

International Journal of Molecular Sciences · 2025 · Vol. 26(5)

Proteomic Insights into Human Limbal Epithelial Progenitor-Derived Small Extracellular Vesicles

Braunsperger, M. V., Martin, G., Herzig, T., Kußberger, I., Gießl, A., Steimle, S., Schlötzer-Schrehardt, U., Schlunck, G., Reinhard, T., & Polisetti, N.

Stem Cell Reviews and Reports · 2025 · Vol. 21

Milk and cheesemaking whey as a sustainable source of extracellular vesicles: Exploring large-scale isolation methods with industrial and potential therapeutic applications

del Saz-Lara, A., López de las Hazas, M.-C., Tomé-Carneiro, J., Mazarío-Gárgoles, C., Gil-Zamorano, J., Balaguer, L., del Pozo-Acebo, L., González-Sarrías, A., Ávila-Gálvez, M. Á., Espín, J. C., Gómez-Coronado, D., Visioli, F., & Dávalos, A.

Pharmacological Research · 2025 · Vol. 220

A novel scalable method for the production of rennet-treated milk-derived extracellular vesicles for improved curcumin oral delivery

Schifano, E., Vari, F., Buccini, L., Karimova, M., Kuanysh Syman, Varnadyan, D., Uccelletti, D., Dinarelli, S., Maurizio Zuccotti, Alfieri, A., Sennato, S., Mura, F., Rossi, M., Dini, L., & Tacconi, S.

Journal of Nanobiotechnology · 2025 · Vol. 23(1)

A promising platform for advancing gene therapy in pancreatic ductal adenocarcinoma

Buocikova, V., Altanerova, U., Soltysova, A., Andrezal, M., Vanova, D., Jakubechova, J., Cihova, M., Burikova, M., Urbanova, M., Juhasikova, L., Drndakova, L., Kajabova, V. H., Demkova, L., Kozovska, Z., Spanik, B., Mego, M., Tomas, M., Dubovan, P., Kolnikova, G., & Novotova, M.

Biomedicine & Pharmacotherapy · 2025 · Vol. 190(118428)

Targeting Oncofoetal Chondroitin Sulphate Allows Identification of Tumour‐Derived Extracellular Vesicles

Enciso‐Martinez, A., Løppke, C., Koene, J. J., Ebbelaar, J., van, Los, M., Emma, Dagil, R., Gustavsson, T., Vidal‐Calvo, E. E., Leeuwen, van, Koning, R. I., Es, N. van, Salanti, A., Edwin, Rienk Nieuwland, Agerbæk, M. Ø., & Dijke, P. ten.

Journal of Extracellular Vesicles · 2025 · Vol. 14(6)

Targeting P2X7 mitigates neurobehavioural alterations in a mouse model of post-acute sequelae of SARS-CoV-2 infection

Szabó, D., Tod, P., Maácz, F., Gölöncsér, F., Iring-Varga, B., Török, B., Zsidei, G., Pályi, B., Kis, Z., & Sperlágh, B.

Neuropharmacology · 2025 · Vol. 278

sEV-ICP-TOF-MS for Multiparametric Single-EV Analysis via Nanoparticle-Conjugated Antibodies and Isotope Ratio Filtering

Kim, M., Ha, S. M., Ha, E., Han, Y., Zayakhuu Gerelkhuu, & Yoon, T. H.

Analytical chemistry · 2025 · Vol. 97(37)

Ginseng-derived exosome-like nanovesicles protect against liver fibrosis by regulating TIMP2 pathways and gut dysbiosis

Kim, J., Sim, Y., Kim, D., Kwon, J., Lee, S., Rungratanawanich, W., Kim, J., Jung, J., Lee, Y., Hyun, S., Lee, S., Kwon, H., Song, B., Seo, K., Kim, D., & Cho, Y.

Asian Journal of Pharmaceutical Sciences · 2025 · Vol. 20(6)

Improvement in Transient Agarose Spot (TAS) Cell Migration Assay: Microplate-Based Detection and Evaluation

Apor Veres-Székely, Csenge Szász, Pap, D., Péter Bokrossy, Dorina Lenzinger, Tamás Visnovitz, Mihály, J., Pálmai, M., Varga, Z., László Őrfi, Szabó, A. J., Ádám Vannay, & Beáta Szebeni.

International Journal of Molecular Sciences · 2025 · Vol. 26(12)

Scalable, High‐Throughput Isolation of Extracellular Vesicles Using Electrokinetic‐Assisted Mesh Filtration: ExoFilter

Lee, K., Bae, M., Kim, Y., Jeon, S., Kang, S., Rhee, W., & Shin, S.

Journal of Extracellular Biology · 2025 · Vol. 4(6)

Quantitative Biodistribution of OMVs Using SPECT/CT Imaging with HYNIC-Duramycin Radiolabeling

Szöllősi, D., Hajdrik, P., Tordai, H., Bergmann, R., Horváth, I., Mihály, J., Gaál, A., Jezsó, B., Shailaja, K. D., Felföldi, T., Padmanabhan, P., Gulyás, B. Z., Máthé, D., Varga, Z., & Szigeti, K.

ACS Omega · 2024 · Vol. 9(42)

Metals in nanomotion: probing the role of extracellular vesicles in intercellular metal transfer

Lei, Q., Phan, T. H., Divakarla, S. K., Kalionis, B., & Chrzanowski, W.

Nanoscale · 2024 · Vol. 16(42)

Biological activities of Citrus-Derived extracellular vesicles on human cells: the role of preservation

Karamanidou, T., Krommydas, K., Karanikou, M., Tsamos, D., Michalakis, K., Kletsas, D., Tsouknidas, A., & Pratsinis, H.

Current Issues in Molecular Biology · 2024 · Vol. 46(6)

Bioprocessing strategies for enhanced probiotic extracellular vesicle production: culture condition modulation

Lei, Q., Divakarla, S. K., Winsley, T., Roux, S., & Chrzanowski, W.

Frontiers in Bioengineering and Biotechnology · 2024 · Vol. 12

Y‐box binding protein 1 in small extracellular vesicles reduces mesenchymal stem cell differentiation to osteoblasts—implications for acute myeloid leukaemia

Chetty, V. K., Ghanam, J., Lichá, K., Brenzel, A., Reinhardt, D., & Thakur, B. K.

Journal of Extracellular Vesicles · 2024 · Vol. 13(3)

Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction

Amaro-Prellezo, E., Gómez-Ferrer, M., Hakobyan, L., Ontoria-Oviedo, I., Peiró-Molina, E., Tarazona, S., Salguero, P., Ruiz-Saurí, A., Selva-Roldán, M., Vives-Sanchez, R., & Sepúlveda, P.

Inflammation and Regeneration · 2024 · Vol. 44(1)

Enrichment, Characterization, and Proteomic Profiling of Small Extracellular Vesicles Derived from Human Limbal Mesenchymal Stromal Cells and Melanocytes

Kistenmacher, S., Schwämmle, M., Martin, G., Ulrich, E., Tholen, S., Schilling, O., Gießl, A., Schlötzer-Schrehardt, U., Bucher, F., Schlunck, G., Nazarenko, I., Reinhard, T., & Polisetti, N.

Cells · 2024 · Vol. 13(7)

Nanoplastics indirectly compromise lettuce growth in hydroponic systems via microbial extracellular vesicles derived from Curvibacter fontanus

Lee, B., Lin, Y., Zheng, Y., Shen, T., Cheng, T., Huang, C., & Hsu, W.

Journal of Hazardous Materials · 2024 · Vol. 480

Unveiling the Immunomodulatory and regenerative potential of iPSC-derived mesenchymal stromal cells and their extracellular vesicles

Buitrago, J. C., Morris, S. L., Backhaus, A., Kaltenecker, G., Kaipa, J. M., Girard, C., Schneider, S., & Gruber, J.

Scientific Reports · 2024 · Vol. 14(1)

TGF‐β regulates the release of breast cancer cell‐derived extracellular vesicles and the sorting of their protein cargo by downregulating RAB27B expression

Li, C., Enciso‐Martinez, A., Koning, R. I., Shahsavari, M., & Dijke, P. T.

Journal of Extracellular Vesicles · 2024 · Vol. 13(12)

Separation of small extracellular vesicles (sEV) from human blood by Superose 6 size exclusion chromatography

Nouvel, J., Quevedo, G. B., Prinz, T., Masood, R., Daaboul, G., Gainey‐Schleicher, T., Wittel, U., Chikhladze, S., Melykuti, B., Helmstaedter, M., Winkler, K., Nazarenko, I., & Pütz, G.

Journal of Extracellular Vesicles · 2024 · Vol. 13(10)

Endoplasmin Is a Hypoxia-Inducible Endoplasmic Reticulum-Derived Cargo of Extracellular Vesicles Released by Cardiac Cell Lines

Koncz A, Turiák L, Németh K, Lenzinger D, Bárkai T, Lőrincz P, Zelenyánszki H, Vukman KV, Buzás EI, Visnovitz T.

Membranes · 2023 · Vol. 13(4)

Extracellular vesicles derived from dental mesenchymal stem/stromal cells with gemcitabine as a cargo have an inhibitory effect on the growth of pancreatic carcinoma cell lines in vitro

Klimova D, Jakubechova J, Altanerova U, Nicodemou A, Styk J, Szemes T, Repiska V, Altaner C.

Molecular and Cellular Probes · 2023 · Vol. 67(101894)

Functional enhancement of exosomes derived from NK cells by IL-15 and IL-21 synergy against hepatocellular carcinoma cells: The cytotoxicity and apoptosis in vitro study

Kim, I., Kim, H. Y., Song, H., Park, J., Choi, Y. H., & Choi, E.

Heliyon · 2023 · Vol. 9(6)

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display

Szöllősi, D., Hajdrik, P., Tordai, H., Horváth, I., Veres, D. S., Gillich, B., Shailaja, K. D., Smeller, L., Bergmann, R., Bachmann, M., Mihály, J., Gaál, A., Jezsó, B., Barátki, B., Kövesdi, D., Bősze, S., Szabó, I., Felföldi, T., Oszwald, E., . . . Szigeti, K.

Scientific Reports · 2023 · Vol. 13(1)

An extensive study of potential inhibitors of extracellular vesicles release in triple-negative breast cancer

McNamee, N., Catalano, M., Mukhopadhya, A., & O’Driscoll, L.

BMC Cancer · 2023 · Vol. 23(1)

Suicide-Gene-Modified extracellular vesicles of human primary uveal melanoma in future therapies

Jakubechova, J., Smolkova, B., Furdova, A., Demkova, L., Altanerova, U., Nicodemou, A., Zeleznikova, T., Klimova, D., & Altaner, C.

International Journal of Molecular Sciences · 2023 · Vol. 24(16)

A Method for Using Cell-Penetrating Peptides for Loading Plasmid DNA into Secreted Extracellular Vesicles

Nebogatova, J., Härk, H. H., Puskar, A., Porosk, L., Guazzi, P., Dowaidar, M., Langel, Ü., & Kurrikoff, K.

Biomolecules · 2023 · Vol. 13(12)

Characterization of bovine uterine fluid extracellular vesicles proteomic profiles at follicular and luteal phases of the oestrous cycle

Piibor, J., Dissanayake, K., Midekessa, G., Andronowska, A., Kavak, A., Waldmann, A., & Fazeli, A.

Veterinary Research Communications · 2022 · Vol. 47(2)

Single-particle detection of native SARS-CoV-2 virions by microfluidic resistive pulse sensing

Varga, Z., Madai, M., Kemenesi, G., Beke-Somfai, T., & Jakab, F.

Colloids and Surfaces B: Biointerfaces · 2022 · Vol. 218

Efficient Small Extracellular Vesicles (EV) Isolation Method and Evaluation of EV-Associated DNA Role in Cell–Cell Communication in Cancer

Chetty VK, Ghanam J, Anchan S, Reinhardt K, Brenzel A, Gelléri M, Cremer C, Grueso-Navarro E, Schneider M, von Neuhoff N, Reinhardt D, Jablonska J, Nazarenko I, Thakur BK

Cancers · 2022 · Vol. 14(9)

New Multiscale Characterization Methodology for Effective Determination of Isolation–Structure–Function Relationship of Extracellular Vesicles

Phan TH, Divakarla SK, Yeo JH, Lei Q, Tharkar P, Pansani TN, Leslie KG, Tong M, Coleman VA, Jämting Å, Du Plessis MD, New EJ, Kalionis B, Demokritou P, Woo HK, Cho YK, Chrzanowski W

Frontiers in Bioengineering and Biotechnology · 2021 · Vol. 9

Plant extracellular vesicles and nanovesicles: Focus on secondary metabolites, proteins and lipids with perspectives on their potential and sources

Woith E, Guerriero G, Hausman JF, Renaut J, Leclercq CC, Weise C, Legay S, Weng A, Melzig MF

International Journal of Molecular Sciences · 2021 · Vol. 22(7)

Extracellular-Vesicle-Based Coatings Enhance Bioactivity of Titanium Implants—SurfEV

Pansani TN, Phan TH, Lei Q, Kondyurin A, Kalionis B, Chrzanowski W.

Nanomaterials · 2021 · Vol. 11(6)

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