Sample type:

EVs containing matrices (i.e. urine, conditioned cell media, plasma, serum)

Quantity:

1 concentrator

Product overview:

  Tangential flow filtration (TFF) is emerging as one of the most efficient methods      for the purification of extracellular vesicles. The TFF-EVs filter allows a rapid,          reproducible and scalable purification of EVs. It can be used on the lab bench for    purifying small volume of samples or connected with a mechanical system for          purifying larger volumes. During the purification, the sample is simultaneously          concentrated. 

  Video guide: https://www.youtube.com/watch?v=D9gBxE6VtXc

Technical Features:

Filter cartridge:

Filtering surface (sqm)

Fiber pore size (nm)           

   Sterilization method 

Hollow fibers made of polyethersulfone

0.025

50 +/- 10

    800

   e-beams sterilization

Sample volume per reaction:

From 10 ml up to 1000 ml

EV recovery:

81%

Concentration time:

5 minutes

Reusable:

Multiple times

Application:

   Fast and scalable EV purification and concentration 

   • Depletion of FBS from bovine EVs 

   • Particle buffer exchange and removal of unbound dye.